癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IL-2R gamma Rabbit pAb
- 产品详情
- 实验流程
| Primary Accession | P31785 |
|---|---|
| Other Accession | P31785 |
| Reactivity | Human |
| Predicted | Rat, Pig, Mouse, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42287 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human IL-2R gamma |
| Epitope Specificity | 51-150/369 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 fibronectin type-III domain. |
| SUBUNIT | The gamma subunit is common to the IL2, IL4, IL7, IL15, IL21 and probably also the IL13 receptors. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010] |
| Gene ID | 3561 |
|---|---|
| Other Names | CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1; IL2RG_HUMAN; IL2RG; Interleukin-2 receptor subunit gamma (IL-2 receptor subunit gamma | IL-2R subunit gamma | IL-2RG); gammaC; interleukin 2 receptor subunit gamma; severe combined immunodeficiency; combined immunodeficiency, X-linked; interleukin 2 receptor, gamma |
| Dilution | ICC/IF=1:100-500,Flow-Cyt=1 µg /test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | IL2RG |
|---|---|
| Function | Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell surface |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP100129
