癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Mast cell tryptase Recombinant Mouse mAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q15661 |
| Other Accession | Q15661 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Recombinant |
| Calculated MW | 30515 Da |
| Physical State | Liquid |
| Immunogen | Recombinant Human Mast cell tryptase protein |
| Isotype | IgG1 |
| Purity | Affinity Purification |
| Buffer | PBS with 100 µg/ml BSA,0.15% ProClin300 and 50% glycerol. |
| SIMILARITY | Belongs to the peptidase S1 family. Tryptase subfamily. Contains 1 peptidase S1 domain. |
| SUBUNIT | Homotetramer. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. |
| Gene ID | 7177 |
|---|---|
| Other Names | TPS1; TPS2; TPSB1; TPSB2; Tryptase-2; MMCP-7; Mcp-7; Mcp7; Mcpt7; rMCP-7; TRYB1_HUMAN; TPSAB1; Tryptase-1; Tryptase I; Tryptase alpha-1; 3.4.21.59; TRYB1_MOUSE; Mast cell protease 7 (mMCP-7); Tryptase alpha/beta-1; TRYB1_RAT; Mast cell protease 7 (rMCP-7); Tryptase, skin; TRYB2_HUMAN; Tryptase II; tryptase alpha/beta 1; tryptase beta 1; tryptase alpha II; tryptase beta I; tryptase-I; tryptase-II; tryptase-III; mast cell tryptase |
| Dilution | IHC-P=1: 100-500,IF=1: 100-500,IHC-F=1: 100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TPSAB1 |
|---|---|
| Synonyms | TPS1, TPS2, TPSB1 |
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315). |
| Cellular Location | Secreted. Note=Released from the secretory granules upon mast cell activation. |
| Tissue Location | Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level) |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
¥ 1,400.00
Cat# AP100153
