癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CD54-AcalephFluor594-labled
- 产品详情
- 实验流程
- 背景知识
Application 
| FC, IF/IC |
|---|---|
| Primary Accession | P13597 |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 58844 Da |
| Gene ID | 15894 |
|---|---|
| Other Names | Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54 |
| Target/Specificity | Recognizes mouse CD54 |
| Dilution | FC~~1:10~50 IF/IC~~N/A |
| Format | Rat IgG2b kappa. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Icam1 {ECO:0000312|MGI:MGI:96392} |
|---|---|
| Function | Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength. Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells. During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. Promotes cell aggregation in epithelial cells through interaction with MUC1. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P05362}; Single-pass type I membrane protein |
| Tissue Location | Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
AcalephFluor594-labled rat monoclonal antibody to CD54
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¥ 900.00
Cat# AP100719
