癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CD16/CD32-AcalephFluor405-labled
- 产品详情
- 实验流程
- 背景知识
Application 
| FC, IF/IC |
|---|---|
| Primary Accession | P08101, P08508 |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 36695 Da |
| Gene ID | 14130 |
|---|---|
| Other Names | CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32 |
| Target/Specificity | Recognizes mouse CD16/CD32 |
| Dilution | FC~~1:10~50 IF/IC~~N/A |
| Format | Rat IgG2a lambda. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Fcgr2 |
|---|---|
| Synonyms | Fcgr2b, Ly-17 |
| Function | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein [Isoform IIB3]: Secreted. Note=Released as a soluble molecule |
| Tissue Location | Widely expressed by cells of hemopoietic origin. The isoforms are differentially expressed. Isoform IIB1 is preferentially expressed by cells of the lymphoid lineage, isoform IIB2 by cells of the myeloid lineage, and isoform IIB3 is released by macrophages and is present in the serum. Isoform IIB1' is expressed in myeloid and lymphoid cell lines, in normal spleen cells, and in resting or LPS-activated B-cells but is not detected in mesenteric lymph node cells |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
AcalephFluor405-labled rat monoclonal antibody to CD16/CD32
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¥ 1,100.00
Cat# AP100987
