癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Integrin beta 7-AcalephFluor647-labled
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- 实验流程
- 背景知识
Application 
| FC, IF/IC |
|---|---|
| Primary Accession | P26010 |
| Other Accession | P26011 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 86903 Da |
| Gene ID | 3695 |
|---|---|
| Other Names | Integrin beta-7; Gut homing receptor beta subunit |
| Target/Specificity | Recognizes human/mouse Integrin beta 7 |
| Dilution | FC~~1:10~50 IF/IC~~N/A |
| Format | Rat IgG2a. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ITGB7 |
|---|---|
| Function | Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract (PubMed:10837471, PubMed:14608374). Also interacts with VCAM1 and fibronectin, an extracellular matrix component (Probable). It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin (Probable). Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin (Probable). Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin (PubMed:10837471). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in a variety of leukocyte lines. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
AcalephFluor647-labled rat monoclonal antibody to Integrin beta 7
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Cat# AP102016
