WFDC12 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB, IHC-P, FC, E |
---|---|
Primary Accession | Q8WWY7 |
Other Accession | NP_543145.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 12050 Da |
Antigen Region | 66-94 aa |
Gene ID | 128488 |
---|---|
Other Names | WAP four-disulfide core domain protein 12, Putative protease inhibitor WAP12, Whey acidic protein 2, WFDC12, C20orf122, WAP2 |
Target/Specificity | This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human WFDC12. |
Dilution | WB~~1:2000 IHC-P~~N/A FC~~1:10~50 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | WFDC12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | WFDC12 |
---|---|
Synonyms | C20orf122, WAP2 |
Function | Antibacterial protein. Putative acid-stable proteinase inhibitor. |
Cellular Location | Secreted. |
Tissue Location | Highly expressed in prostate, skin, lung and esophagus. Weakly expressed in skeletal muscle, epididymis, kidney, trachea, salivary gland, testis and seminal vesicle |
For Research Use Only. Not For Use In Diagnostic Procedures.

Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
REFERENCES
Clauss, A., et al. Biochem. Biophys. Res. Commun. 333(2):383-389(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Clauss, A., et al. Biochem. J. 368 (PT 1), 233-242 (2002) :
Lundwall, A., et al. Biochem. Biophys. Res. Commun. 290(1):452-456(2002)
Deloukas, P., et al. Nature 414(6866):865-871(2001)

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