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FAM46A Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - FAM46A Antibody (Center) AP10394c
    FAM46A Antibody (Center) (Cat. #AP10394c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FAM46A antibody detected the FAM46A protein (arrow).
  • 14 - FAM46A Antibody (Center) AP10394c
    FAM46A antibody (Center) (Cat. #AP10394c) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FAM46A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q96IP4
Other Accession NP_060103.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 49666 Da
Antigen Region 89-117 aa
Additional Information
Gene ID 55603
Other Names Protein FAM46A, HBV X-transactivated gene 11 protein, HBV XAg-transactivated protein 11, FAM46A, C6orf37, XTP11
Target/Specificity This FAM46A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the Central region of human FAM46A.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFAM46A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TENT5A (HGNC:18345)
Function Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:D3Z5S8}.
Tissue Location Widely expressed, with preferential expression observed in the retina compared to other ocular tissues (PubMed:12054608). Also expressed in osteoblasts (PubMed:29358272)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Barragan, I., et al. Ann. Hum. Genet. 72 (PT 1), 26-34 (2008) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Cui, J., et al. Zhejiang Da Xue Xue Bao Yi Xue Ban 35(4):354-359(2006)
Cui, J., et al. Clin. Chim. Acta 368 (1-2), 155-159 (2006) :
Lim, J., et al. Cell 125(4):801-814(2006)

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