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RASAL3 Antibody (C-term) 精选

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RASAL3 Antibody (C-term) AP10598b
    RASAL3 Antibody (C-term) (Cat. #AP10598b) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the RASAL3 antibody detected the RASAL3 protein (arrow).
  • 14 - RASAL3 Antibody (C-term) AP10598b
    RASAL3 Antibody (C-term)(Cat. #AP10598b) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RASAL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q86YV0
Other Accession NP_075055.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 111898 Da
Antigen Region 947-975 aa
Additional Information
Gene ID 64926
Other Names RAS protein activator like-3, RASAL3
Target/Specificity This RASAL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 947-975 amino acids from the C-terminal region of human RASAL3.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRASAL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name RASAL3
Function Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down- stream ERK signaling pathway.
Cellular Location Cytoplasm. Cytoplasm, cell cortex
Tissue Location Predominantly expressed in cells of hematopoietic lineages.
Research Areas

BACKGROUND

May functions as a Ras GTPase-activating protein (By similarity).

REFERENCES

Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)

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