癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DNAJB13 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P59910 |
| Other Accession | Q80Y75, NP_705842.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36118 Da |
| Antigen Region | 176-205 aa |
| Gene ID | 374407 |
|---|---|
| Other Names | DnaJ homolog subfamily B member 13, Testis and spermatogenesis cell-related protein 6, Testis spermatocyte apoptosis-related gene 6 protein, Testis spermatogenesis apoptosis-related gene 3 protein, Testis spermatogenesis apoptosis-related gene 6 protein, DNAJB13, TSARG3, TSARG6 |
| Target/Specificity | This DNAJB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the Central region of human DNAJB13. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DNAJB13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNAJB13 |
|---|---|
| Synonyms | TSARG3, TSARG6 |
| Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. |
| Cellular Location | Cell projection, cilium, flagellum. Note=Localizes both to epithelial motile cilium and the sperm flagellum (PubMed:27486783). In spermatids, rapidly enriched in the coupling apparatus with the elongation of the spermatid. Tightly attached to the implantation fossa during the maturation of the spermatid. In mature spermatzoa evenly distributed along the flagellum (By similarity). {ECO:0000250|UniProtKB:Q80Y75, ECO:0000269|PubMed:27486783} |
| Tissue Location | Specifically expressed in testis and trachea. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
DNAJA13 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family, see 608375.
REFERENCES
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Liu, G., et al. Acta Biochim. Biophys. Sin. (Shanghai) 36(2):93-98(2004)
Liu, G., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20(2):107-110(2003)
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