SHISA6 Antibody (N-term) 精选

Affinity Purified Rabbit Polyclonal Antibody (Pab)

SHISA6 Antibody (N-term) (Cat. #AP11913a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SHISA6 antibody detected the SHISA6 protein (arrow).
SHISA6 Antibody (N-term) (Cat. #AP11913a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SHISA6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	Q6ZSJ9
Other Accession	Q3UH99, NP_997269.2
Reactivity	Human
Predicted	Mouse, Rat, Bovine, Canine, Rabbit, Chicken
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Calculated MW	55764 Da
Antigen Region	81-109 aa

Additional Information
Gene ID	388336
Other Names	Protein shisa-6 homolog, SHISA6
Target/Specificity	This SHISA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human SHISA6.
Dilution	WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration.
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions	SHISA6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	SHISA6 (HGNC:34491)
Function	Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway.
Cellular Location	Membrane; Single-pass type I membrane protein {ECO:0000250\|UniProtKB:Q3UH99}. Postsynaptic density {ECO:0000250\|UniProtKB:Q3UH99}
Tissue Location	Expressed in the developing ventral mesencephalon.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.