DVL3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IHC-P, IF, WB, E |
---|---|
Primary Accession | Q92997 |
Other Accession | Q61062, NP_004414.3 |
Reactivity | Human, Mouse |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 78055 Da |
Antigen Region | 530-557 aa |
Gene ID | 1857 |
---|---|
Other Names | Segment polarity protein dishevelled homolog DVL-3, Dishevelled-3, DSH homolog 3, DVL3, KIAA0208 |
Target/Specificity | This DVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the C-terminal region of human DVL3. |
Dilution | IHC-P~~1:100~500 IF~~1:10~50 WB~~1:2000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DVL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DVL3 |
---|---|
Synonyms | KIAA0208 |
Function | Involved in the signal transduction pathway mediated by multiple Wnt genes. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O14641}. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
REFERENCES
Gnad, T., et al. Mol. Cancer 9, 31 (2010) :
Bouteille, N., et al. Oncogene 28(28):2569-2580(2009)
Fukukawa, C., et al. Oncogene 28(8):1110-1120(2009)
Wei, Q., et al. Lung Cancer 62(2):181-192(2008)
Lee, Y.N., et al. Cell. Signal. 20(2):443-452(2008)

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