癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GPD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 1
- 实验流程
- 背景知识
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P43304 |
| Other Accession | Q64521, Q4R755, A6QLU1 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 80853 Da |
| Antigen Region | 606-634 aa |
| Gene ID | 2820 |
|---|---|
| Other Names | Glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M, mtGPD, GPD2 |
| Target/Specificity | This GPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-634 amino acids from the C-terminal region of human GPD2. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPD2 (HGNC:4456) |
|---|---|
| Function | Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta- cell glucose-sensing device. |
| Cellular Location | Mitochondrion. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.
REFERENCES
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Daoud, H., et al. Hum. Genet. 124(6):649-658(2009)
Chowdhury, S.K., et al. Free Radic. Res. 41(10):1116-1124(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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