癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CLEC3B Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 1
- 实验流程
- 背景知识
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | P05452 |
| Other Accession | Q2KIS7, NP_003269.2 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22537 Da |
| Antigen Region | 95-122 aa |
| Gene ID | 7123 |
|---|---|
| Other Names | Tetranectin, TN, C-type lectin domain family 3 member B, Plasminogen kringle 4-binding protein, CLEC3B, TNA |
| Target/Specificity | This CLEC3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from the Central region of human CLEC3B. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CLEC3B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLEC3B |
|---|---|
| Synonyms | TNA |
| Function | Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Plays a role in retinal function (PubMed:35331648). |
| Cellular Location | Secreted. |
| Tissue Location | Found in plasma. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Tetranectin binds to plasminogen and to isolated kringle 4. It may be involved in the packaging of molecules destined for exocytosis.
REFERENCES
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Valdes, A.M., et al. Arthritis Rheum. 54(2):533-539(2006)
Hermann, M., et al. Transplant. Proc. 37(2):1322-1325(2005)
Anderson, N.L., et al. Mol. Cell Proteomics 3(4):311-326(2004)
Westergaard, U.B., et al. Eur. J. Biochem. 270(8):1850-1854(2003)
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