癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TNMD Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 1
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H2S6 |
| Other Accession | NP_071427.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37130 Da |
| Antigen Region | 213-241 aa |
| Gene ID | 64102 |
|---|---|
| Other Names | Tenomodulin, TeM, hTeM, Chondromodulin-1-like protein, ChM1L, hChM1L, Chondromodulin-I-like protein, Myodulin, Tendin, TNMD, CHM1L |
| Target/Specificity | This TNMD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the Central region of human TNMD. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TNMD Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNMD |
|---|---|
| Synonyms | CHM1L |
| Function | May be an angiogenesis inhibitor. |
| Cellular Location | [Isoform 1]: Membrane; Single-pass type II membrane protein. Nucleus envelope [Isoform 3]: Cytoplasm. |
| Tissue Location | Highly expressed in hypovascular connective tissues such as tendons. Also has strong expression in adipose tissue |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.
REFERENCES
Saiki, A., et al. J. Clin. Endocrinol. Metab. 94(10):3987-3994(2009)
Tolppanen, A.M., et al. Neurobiol. Aging (2009) In press :
Tolppanen, A.M., et al. Mol. Vis. 15, 762-770 (2009) :
Tolppanen, A.M., et al. Int J Obes (Lond) 32(12):1868-1872(2008)
Kimura, N., et al. Circulation 118(17):1737-1747(2008)
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
