癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Drosophila SUMO Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 2
- 实验流程
- 背景知识
Application 
| IF, E |
|---|---|
| Primary Accession | O97102 |
| Reactivity | Human, Drosophila |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 10124 Da |
| Gene ID | 33981 |
|---|---|
| Other Names | CG4494-PA; LD07775p; Smt3; Ubiquitin-like protein SMT3 |
| Target/Specificity | This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila SUMO1. |
| Dilution | IF~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Drosophila SUMO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | O97102 |
|---|---|
| Cellular Location | Nucleus {ECO:0000256|RuleBase:RU361190}. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
REFERENCES
Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review. Hochstrasser M. Cell. 2001 107(1):5-8. Review. Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8. Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review. Keane,M.M., et al., Oncogene 18 (22), 3365-3375 (1999)
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