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PITPNB Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PITPNB Antibody (C-term) AP12982b
    PITPNB Antibody (C-term) (Cat. #AP12982b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PITPNB antibody detected the PITPNB protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P48739
Other Accession P53812, P53811, Q9TR36, NP_036531.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31540 Da
Antigen Region 226-254 aa
Additional Information
Gene ID 23760
Other Names Phosphatidylinositol transfer protein beta isoform, PI-TP-beta, PtdIns transfer protein beta, PtdInsTP beta, PITPNB
Target/Specificity This PITPNB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human PITPNB.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPITPNB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PITPNB
Function Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (PubMed:10531358, PubMed:18636990, PubMed:20332109). Also catalyzes the transfer of sphingomyelin (By similarity). Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function (PubMed:20332109).
Cellular Location Golgi apparatus {ECO:0000250|UniProtKB:P53811}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P53812}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P53812}
Tissue Location Widely expressed in various tissues including brain
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.

REFERENCES

Carvou, N., et al. J. Cell. Sci. 123 (PT 8), 1262-1273 (2010) :
Morgan, C.P., et al. Biochem. J. 398(3):411-421(2006)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Segui, B., et al. Biochem. J. 366 (PT 1), 23-34 (2002) :

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