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>   首页   >   产品   >   一抗   >   癌症   >   LNX2 Antibody (C-term)   

LNX2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - LNX2 Antibody (C-term) AP13071b
    LNX2 Antibody (C-term) (Cat. #AP13071b) western blot analysis in HepG2,293,NCI-H460 cell line lysates (35ug/lane).This demonstrates the LNX2 antibody detected the LNX2 protein (arrow).
  • 14 - LNX2 Antibody (C-term) AP13071b
    LNX2 Antibody (C-term) (Cat. #AP13071b)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LNX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q8N448
Other Accession NP_699202.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 76004 Da
Additional Information
Gene ID 222484
Other Names Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1
Target/Specificity This LNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human LNX2.
Dilution WB~~1:1000
IHC-P~~1:100~500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLNX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LNX2
Synonyms PDZRN1
Research Areas

BACKGROUND

LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.

REFERENCES

Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)
Sullivan, P.F., et al. Mol. Psychiatry 13(6):570-584(2008)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Rice, D.S., et al. Mol. Cell. Neurosci. 18(5):525-540(2001)

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