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C17orf95 Antibody (C-term) 精选

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - C17orf95 Antibody (C-term) AP13464b
    All lanes : Anti-C17orf95 Antibody (C-term) at 1:500 dilution Lane 1: A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution. Observed band size : 28kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - C17orf95 Antibody (C-term) AP13464b
    All lanes : Anti-C17orf95 Antibody (C-term) at 1:500 dilution Lane 1: A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution. Observed band size : 30kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - C17orf95 Antibody (C-term) AP13464b
    All lanes : Anti-FUNDC2 Antibody (C-term) at 1:1000 dilution Lane 1: NCI-H460 whole cell lysate Lane 2: U-251 MG whole cell lysate Lane 3: 293 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution. Observed band size : 29kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - C17orf95 Antibody (C-term) AP13464b
    C17orf95 Antibody (C-term) (Cat. #AP13464b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the C17orf95 antibody detected the C17orf95 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q86XA0
Other Accession Q5RJL2, A2AA28, NP_001073979.2
Reactivity Human, Rat, Mouse
Predicted Mouse, Rat, Bovine, Canine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21469 Da
Antigen Region 138-166 aa
Additional Information
Gene ID 124512
Other Names Methyltransferase-like protein 23, 211-, METTL23, C17orf95
Target/Specificity This C17orf95 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the C-terminal region of human C17orf95.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC17orf95 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name METTL23 {ECO:0000303|PubMed:24501276, ECO:0000312|HGNC:HGNC:26988}
Function Histone methyltransferase that dimethylates histone H3 at 'Arg-17', forming asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling (By similarity). Maternal factor involved in epigenetic chromatin reprogramming of the paternal genome in the zygote: mediates H3R17me2a, promoting histone H3.3 incorporation in the male pronucleus, leading to TET3 recruitment and subsequent DNA demethylation (By similarity).
Cellular Location Nucleus. Cytoplasm Note=Localizes in male and female zygote pronucleus and cytoplasm {ECO:0000250|UniProtKB:A2AA28}
Research Areas

BACKGROUND

The specific function of the protein remains unknown.

REFERENCES

Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)

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