癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IL9R Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q01113 |
| Other Accession | NP_002177.2 |
| Reactivity | Human, Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 57147 Da |
| Antigen Region | 170-199 aa |
| Gene ID | 3581 |
|---|---|
| Other Names | Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129, IL9R |
| Target/Specificity | This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IL9R Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL9R |
|---|---|
| Function | Plays an important role in the immune response against parasites by acting as a receptor of IL9. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
REFERENCES
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
McCanlies, E.C., et al. J. Occup. Environ. Med. 52(7):680-684(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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