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>   首页   >   产品   >   一抗   >   癌症   >   FDFT1 Antibody (C-term)   

FDFT1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - FDFT1 Antibody (C-term) AP14561b
    FDFT1 Antibody (C-term) (Cat. #AP14561b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FDFT1 antibody detected the FDFT1 protein (arrow).
  • 1 - FDFT1 Antibody (C-term) AP14561b
    Western blot analysis of FDFT1 (arrow) using rabbit polyclonal FDFT1 Antibody (C-term) (Cat. #AP14561b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDFT1 gene.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P37268
Other Accession NP_004453.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Antigen Region 332-361 aa
Additional Information
Other Names Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1
Target/Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFDFT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

REFERENCES

Chalasani, N., et al. Gastroenterology 139(5):1567-1576(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010)
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Sjoholm, L.K., et al. J Circadian Rhythms 8, 1 (2010) :

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