PGF Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | P49763 |
Other Accession | NP_002623.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24789 Da |
Antigen Region | 120-148 aa |
Gene ID | 5228 |
---|---|
Other Names | Placenta growth factor, PlGF, PGF, PGFL, PLGF |
Target/Specificity | This PGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human PGF. |
Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PGF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PGF |
---|---|
Synonyms | PGFL, PLGF |
Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. |
Cellular Location | Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin |
Tissue Location | While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.

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Cat# AP14578c