癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CSDA Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | P16989 |
| Other Accession | Q62764, Q9JKB3, NP_001138898.1, NP_003642.3 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40090 Da |
| Antigen Region | 152-181 aa |
| Gene ID | 8531 |
|---|---|
| Other Names | Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Single-strand DNA-binding protein NF-GMB, YBX3, CSDA, DBPA |
| Target/Specificity | This CSDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of human CSDA. |
| Dilution | WB~~1:500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CSDA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | YBX3 |
|---|---|
| Synonyms | CSDA, DBPA |
| Function | Binds to the GM-CSF promoter. Seems to act as a repressor. Also binds to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. |
| Tissue Location | Highly expressed in skeletal muscle and heart. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
REFERENCES
Lima, W.R., et al. J. Am. Soc. Nephrol. 21(3):478-488(2010)
Wang, G.R., et al. Acta Pharmacol. Sin. 30(10):1436-1442(2009)
Sharpe Elles, L.M., et al. Nucleic Acids Res. 37(19):6503-6514(2009)
Buchert, M., et al. Gastroenterology 137(1):156-164(2009)
Hayashi, J., et al. Int. J. Oncol. 21(4):847-850(2002)
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