癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FAU Antibody (C-term) 精选
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P62861 |
| Other Accession | P62864, P62863, P62862, P62861, P62860, P62866, NP_001988 |
| Reactivity | Human, Rat, Mouse |
| Predicted | Bovine, Hamster, Mouse, Pig, Rat, Canine, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 14390 Da |
| Antigen Region | 29-59 aa |
| Gene ID | 2197 |
|---|---|
| Other Names | 40S ribosomal protein S30, FAU |
| Target/Specificity | This FAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the C-terminal region of human FAU. |
| Dilution | IHC-P~~1:100~500 WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FAU Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | FAU (HGNC:3597) |
|---|---|
| Function | [Ubiquitin-like protein FUBI]: May have pro-apoptotic activity. |
| Cellular Location | [Small ribosomal subunit protein eS30]: Cytoplasm. Nucleus |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.
REFERENCES
Rossman, T.G., et al., Oncogene 22(12):1817-1821 (2003).
Kenmochi, N., et al., Genome Res. 8(5):509-523 (1998).
Vladimirov, S.N., et al., Eur. J. Biochem. 239(1):144-149 (1996).
Kas, K., et al., Genomics 17(2):387-392 (1993).
Michiels, L., et al., Oncogene 8(9):2537-2546 (1993).
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