癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
BTN2A1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q7KYR7 |
| Other Accession | NP_008980.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59633 Da |
| Antigen Region | 344-373 aa |
| Gene ID | 11120 |
|---|---|
| Other Names | Butyrophilin subfamily 2 member A1, BTN2A1, BT21, BTF1 |
| Target/Specificity | This BTN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human BTN2A1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BTN2A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BTN2A1 |
|---|---|
| Synonyms | BT2.1, BTF1 |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
BTN2A1 is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
Malcherek, G., et al. J. Immunol. 179(6):3804-3811(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Rhodes, D.A., et al. Genomics 71(3):351-362(2001)
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