癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TMPRSS11E Antibody (Center) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UL52 |
| Other Accession | NP_054777.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat, Bovine, Canine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47696 Da |
| Antigen Region | 249-277 aa |
| Gene ID | 28983 |
|---|---|
| Other Names | Transmembrane protease serine 11E, 3421-, Serine protease DESC1, Transmembrane protease serine 11E2, Transmembrane protease serine 11E non-catalytic chain, Transmembrane protease serine 11E catalytic chain, TMPRSS11E, DESC1, TMPRSS11E2 |
| Target/Specificity | This TMPRSS11E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human TMPRSS11E. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TMPRSS11E Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TMPRSS11E |
|---|---|
| Synonyms | DESC1, TMPRSS11E2 |
| Function | Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q5S248}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q5S248} |
| Tissue Location | Expression can only be detected in tissues derived from the head and neck, and in skin, prostate and testis |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
TMPRSS11E is serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position (By similarity).
REFERENCES
Kyrieleis, O.J., et al. FEBS J. 274(8):2148-2160(2007)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Hobson, J.P., et al. J. Biol. Chem. 279(45):46981-46994(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Lang, J.C., et al. Br. J. Cancer 84(2):237-243(2001)
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