癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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SRRD Antibody (Center) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UH36 |
| Other Accession | NP_001013716.2 |
| Reactivity | Human |
| Predicted | Mouse, Canine, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38573 Da |
| Antigen Region | 184-213 aa |
| Gene ID | 402055 |
|---|---|
| Other Names | SRR1-like protein, SRR1 domain-containing protein, SRRD, SRR1L |
| Target/Specificity | This SRRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human SRRD. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SRRD Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SRRD |
|---|---|
| Synonyms | SRR1L |
| Function | Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q8K2M3}. Note=Also found in intracellular organelles {ECO:0000250|UniProtKB:Q8K2M3} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
SRRD may be involved in a circadian clock input pathway (By similarity).
REFERENCES
Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008)
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kedar, V., et al. Biochem. Biophys. Res. Commun. 226(2):461-466(1996)
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