癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Mouse Stk32a Antibody (C-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q8BGW6 |
| Other Accession | XP_001477653.1 |
| Reactivity | Human, Mouse |
| Predicted | Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46509 Da |
| Antigen Region | 347-374 aa |
| Gene ID | 269019 |
|---|---|
| Other Names | Serine/threonine-protein kinase 32A, Stk32a {ECO:0000312|MGI:MGI:2442403} |
| Target/Specificity | This Mouse Stk32a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-374 amino acids from the C-terminal region of mouse Stk32a. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Stk32a Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Stk32a {ECO:0000312|MGI:MGI:2442403} |
|---|---|
| Function | Probable serine/threonine kinase with currently unidentified substrates. In the inner ear, functions as a planar cell polarity (PCP) factor acting antagonistically to EMX2. It regulates the orientation of stereociliary bundles in hair cells by interacting with the PCP signaling pathway in opposition to EMX2 (PubMed:37144879). Additionally, it may play a role in controlling the apical localization of the GPR156 receptor in inner ear hair cells (PubMed:37144879). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8WU08}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WU08} |
| Tissue Location | Expressed in hair cells on one side of the line of polarity reversal (LPR) in a pattern complementary to Emx2 expression in hair cells on the opposite side. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
STK32A is a member ot the serine/threonine protein kinase family. The specific function of this kinase is not known.
REFERENCES
Gallardo, T.D., et al. Genetics 177(1):179-194(2007)
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