癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TAS2R10 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q9NYW0 |
| Other Accession | NP_076410.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35365 Da |
| Antigen Region | 134-160 aa |
| Gene ID | 50839 |
|---|---|
| Other Names | Taste receptor type 2 member 10, T2R10, Taste receptor family B member 2, TRB2, TAS2R10 |
| Target/Specificity | This TAS2R10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human TAS2R10. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TAS2R10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TAS2R10 |
|---|---|
| Function | Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
REFERENCES
Go, Y., et al. Genetics 170(1):313-326(2005)
Mueller, K.L., et al. Nature 434(7030):225-229(2005)
Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)
Zhang, Y., et al. Cell 112(3):293-301(2003)
Montmayeur, J.P., et al. Curr. Opin. Neurobiol. 12(4):366-371(2002)
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