癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MS4A6A Antibody (N-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q9H2W1 |
| Other Accession | Q96DS6, NP_071744.2 |
| Reactivity | Human |
| Predicted | Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26943 Da |
| Antigen Region | 11-38 aa |
| Gene ID | 64231 |
|---|---|
| Other Names | Membrane-spanning 4-domains subfamily A member 6A, CD20 antigen-like 3, Four-span transmembrane protein 3, MS4A6A, 4SPAN3, CD20L3, MS4A6 |
| Target/Specificity | This MS4A6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-38 amino acids from the N-terminal region of human MS4A6A. |
| Dilution | WB~~1:500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MS4A6A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MS4A6A |
|---|---|
| Synonyms | 4SPAN3, CD20L3, MS4A6 |
| Function | May be involved in signal transduction as a component of a multimeric receptor complex. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants.
REFERENCES
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Liang, Y., et al. Immunogenetics 53(5):357-368(2001)
Liang, Y., et al. Genomics 72(2):119-127(2001)
Ishibashi, K., et al. Gene 264(1):87-93(2001)
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