|Application ||IHC-P-Leica, WB, E|
|Calculated MW||100677 Da|
|Other Names||OTU domain-containing protein 7A, Zinc finger protein Cezanne 2, OTUD7A, C15orf16, CEZANNE2, OTUD7|
|Target/Specificity||This OTUD7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human OTUD7A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OTUD7A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C15orf16, CEZANNE2, OTUD7|
|Function||Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains.|
|Cellular Location||Cytoplasm. Nucleus|
Provided below are standard protocols that you may find useful for product applications.
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM].
Morrison, A.C., et al. Circ Cardiovasc Genet 3(3):248-255(2010)