癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
BTG4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q9NY30 |
| Other Accession | NP_060059.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25970 Da |
| Antigen Region | 142-169 aa |
| Gene ID | 54766 |
|---|---|
| Other Names | Protein BTG4, BTG family member 4, Protein PC3b, BTG4, PC3B |
| Target/Specificity | This BTG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the C-terminal region of human BTG4. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BTG4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BTG4 |
|---|---|
| Synonyms | PC3B |
| Function | Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E (By similarity). Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development (PubMed:32502391). |
| Tissue Location | Expressed in oocytes after germinal vesicle breakdown (PubMed:32502391). Expressed in testis and in olfactory epithelium. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle.
REFERENCES
Xu, Y., et al. Int. J. Cancer (2010) In press :
Dong, W., et al. Biochem. Biophys. Res. Commun. 387(1):132-138(2009)
Toyota, M., et al. Cancer Res. 68(11):4123-4132(2008)
Auer, R.L., et al. Genes Chromosomes Cancer 43(1):1-10(2005)
Yoshida, Y., et al. Jpn. J. Cancer Res. 92(6):592-596(2001)
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