癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FUBP3 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q96I24 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61640 Da |
| Antigen Region | 38-67 aa |
| Gene ID | 8939 |
|---|---|
| Other Names | Far upstream element-binding protein 3, FUSE-binding protein 3, FUBP3, FBP3 |
| Target/Specificity | This FUBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human FUBP3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FUBP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FUBP3 |
|---|---|
| Synonyms | FBP3 |
| Function | May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. |
| Cellular Location | Nucleus. |
| Tissue Location | Detected in a number of cell lines. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The far upstream element-binding proteins FUBP, FUBP2, and FUBP3 comprise a family of single-strand DNA-binding proteins that possess all of the general features of more conventional transcription factors. The FUBPs each bind to a single sequence-specific strand of the far upstream element (FUSE; originally identified upstream of c-myc), and each possesses potent activation domains when fused to the GAL4 DNA-binding domain and assayed by transient transfection. These proteins have also been reported to bind RNA and participate in various steps of RNA processing, transport or catabolism.
REFERENCES
He L, et al. Nucleic Acids Res. 2000 Nov 15;28(22):4558-65.
Davis-Smyth T, et al. J Biol Chem. 1996 Dec 6;271(49):31679-87.
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