癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TSGA10 Antibody(N-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BZW7 |
| Other Accession | NP_079520.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 81421 Da |
| Antigen Region | 37-63 aa |
| Gene ID | 80705 |
|---|---|
| Other Names | Testis-specific gene 10 protein, Testis development protein NYD-SP7, TSGA10, CEP4L |
| Target/Specificity | This TSGA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-63 amino acids from the N-terminal region of human TSGA10. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TSGA10 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TSGA10 |
|---|---|
| Synonyms | CEP4L |
| Function | Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9Z220}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). {ECO:0000250|UniProtKB:Q9Z220, ECO:0000269|PubMed:28905369} |
| Tissue Location | Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816). |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
TSGA10 may play a role in the sperm tail fibrous sheath, a major sperm tail structure (By similarity).
REFERENCES
Roghanian, A., et al. Cell. Immunol. 265(2):120-126(2010)
Reimand, K., et al. Int. Immunol. 20(1):39-44(2008)
Mobasheri, M.B., et al. Leuk. Res. 30(7):883-889(2006)
Tanaka, R., et al. Microbiol. Immunol. 48(4):339-345(2004)
Modarressi, M.H., et al. Gene 262 (1-2), 249-255 (2001) :
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