TAAR2 Antibody (N-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9P1P5 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40134 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 9287 |
|---|---|
| Other Names | Trace amine-associated receptor 2, TaR-2, Trace amine receptor 2, G-protein coupled receptor 58, TAAR2, GPR58 |
| Target/Specificity | This TAAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAAR2. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TAAR2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TAAR2 {ECO:0000303|PubMed:15718104, ECO:0000312|HGNC:HGNC:4514} |
|---|---|
| Function | Orphan olfactory receptor specific for trace amines. Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors. Ligand-binding causes a conformation change that triggers signaling via the G(s)-class of G proteins which activate adenylate cyclase. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q5QD04}; Multi-pass membrane protein |
| Tissue Location | Not expressed in the pons, thalamus, hypothalamus, hippocampus, caudate, putamen, frontal cortex, basal forebrain, midbrain or liver. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Orphan receptor.
REFERENCES
Lee D.K., et al. Biochim. Biophys. Acta 1490:311-323(2000).
Lindemann L., et al. Genomics 85:372-385(2005).
Mungall A.J., et al. Nature 425:805-811(2003).
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