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TREX2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - TREX2 Antibody (C-term) AP21082a
    Western blot analysis of lysate from HL-60 cell line, using TREX2 Antibody (C-term)(Cat. #AP21082a). AP21082a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9BQ50
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 25922 Da
Additional Information
Gene ID 11219
Other Names Three prime repair exonuclease 2, 3'-5' exonuclease TREX2, TREX2
Target/Specificity This TREX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 264-299 amino acids from the C-terminal region of human TREX2.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTREX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TREX2
Function Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Cellular Location Nucleus.
Tissue Location Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.

REFERENCES

Mazur D.J.,et al.J. Biol. Chem. 274:19655-19660(1999).
Mazur D.J.,et al.J. Biol. Chem. 276:14718-14727(2001).
Mazur D.J.,et al.J. Biol. Chem. 276:17022-17029(2001).
Perrino F.W.,et al.J. Biol. Chem. 280:15212-15218(2005).

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