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SSTR1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SSTR1 Antibody (C-term) AP21173a
    Anti-SSTR1 Antibody (C-term) at 1:4000 dilution + THP-1 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - SSTR1 Antibody (C-term) AP21173a
    All lanes : Anti-SSTR1 Antibody (C-term) at 1:4000 dilution Lane 1: human pancreas lysates Lane 2: human lung lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P30872
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 42686 Da
Additional Information
Gene ID 6751
Other Names Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SRIF-2, SSTR1
Target/Specificity This SSTR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-403 amino acids from the C-terminal region of human SSTR1.
Dilution WB~~1:4000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSTR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSTR1
Function Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.

REFERENCES

Yamada Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:251-255(1992).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Schwaerzler A.,et al.J. Biol. Chem. 275:9557-9562(2000).

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