癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DIP2A Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q14689 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 170369 Da |
| Gene ID | 23181 |
|---|---|
| Other Names | Disco-interacting protein 2 homolog A, DIP2 homolog A, DIP2A, C21orf106, DIP2, KIAA0184 |
| Target/Specificity | This DIP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 934-969 amino acids from the Central region of human DIP2A. |
| Dilution | WB~~1:1000-1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DIP2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DIP2A |
|---|---|
| Synonyms | C21orf106, DIP2, KIAA0184 |
| Function | Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002). |
| Cellular Location | Cell membrane; Peripheral membrane protein. Mitochondrion {ECO:0000250|UniProtKB:Q8BWT5}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q8BWT5} |
| Tissue Location | Low expression in all tissues tested. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
May provide positional cues for axon pathfinding and patterning in the central nervous system.
REFERENCES
Gardiner K.,et al.Genomics 79:833-843(2002).
Tanaka M.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hattori M.,et al.Nature 405:311-319(2000).
Nagase T.,et al.DNA Res. 3:17-24(1996).
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¥ 1,250.00
Cat# AP21444c
