Zebrafish wnt8b Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB, E |
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Primary Accession | P51029 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 40343 Da |
Gene ID | 30144 |
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Other Names | Protein Wnt-8b, wnt8b, wnt-8b |
Target/Specificity | This Zebrafish wnt8b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 201-235 amino acids from the central region of Zebrafish wnt8b. |
Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Zebrafish wnt8b Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | wnt8b |
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Synonyms | wnt-8b |
Function | Ligand for fzd8a, a member of the G-protein coupled frizzled receptor family (Probable). May play a role in the establishment of polarity in the nervous system. Involved in canonical Wnt signaling pathway. During embryonic development, required for the acquisition of caudal diencephalic fate. Antagonizes eye specification (PubMed:15996547). |
Cellular Location | Secreted, extracellular space, extracellular matrix |
Tissue Location | Hindbrain r1, 2 and 5. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May play a role in the establishment of polarity in the nervous system.
REFERENCES
Kelly G.M.,et al.Development 121:1787-1799(1995).

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