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MPP2 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MPP2 Antibody (C-Term) AP21878b
    Anti-MPP2 Antibody (C-Term) at 1:2000 dilution + mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 65 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q14168
Other Accession Q9WV34
Reactivity Human, Mouse
Predicted Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 64581 Da
Additional Information
Gene ID 4355
Other Names MAGUK p55 subfamily member 2, Discs large homolog 2, Protein MPP2, MPP2, DLG2
Target/Specificity This MPP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 398-419 amino acids from human MPP2.
Dilution WB~~1:2000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMPP2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPP2 (HGNC:7220)
Synonyms DLG2
Function Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2- containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017).
Cellular Location Cytoplasm, cytoskeleton. Membrane Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Postsynaptic density {ECO:0000250|UniProtKB:Q9WV34}. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. {ECO:0000250|UniProtKB:Q9WV34}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Mazoyer S.,et al.Genomics 28:25-31(1995).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

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