癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HMG20B Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q9P0W2 |
| Other Accession | Q32L68 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35813 Da |
| Gene ID | 10362 |
|---|---|
| Other Names | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein, BRCA2-associated factor 35, HMG box-containing protein 20B, HMG domain-containing protein 2, HMG domain-containing protein HMGX2, Sox-like transcriptional factor, Structural DNA-binding protein BRAF35, HMG20B, BRAF35, HMGX2, HMGXB2, SMARCE1R |
| Target/Specificity | This HMG20B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-43 amino acids from human HMG20B. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HMG20B Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HMG20B |
|---|---|
| Synonyms | BRAF35, HMGX2, HMGXB2, SMARCE1R |
| Function | Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. |
| Cellular Location | Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2 |
| Tissue Location | Ubiquitously expressed in adult tissues. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
REFERENCES
Sumoy L.,et al.Cytogenet. Cell Genet. 88:62-67(2000).
Marmorstein L.Y.,et al.Cell 104:247-257(2001).
Lee Y.M.,et al.Biochim. Biophys. Acta 1574:269-276(2002).
Wang C.,et al.Biochem. Biophys. Res. Commun. 295:129-135(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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