癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
USP32 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NFA0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 181656 Da |
| Gene ID | 84669 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 32, 3.4.19.12, Deubiquitinating enzyme 32, Renal carcinoma antigen NY-REN-60, Ubiquitin thioesterase 32, Ubiquitin-specific-processing protease 32, USP32, USP10 |
| Target/Specificity | This USP32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 438-470 amino acids from human USP32. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | USP32 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | USP32 |
|---|---|
| Synonyms | USP10 |
| Function | Deubiquitinase that can remove conjugated ubiquitin from target proteins, such as RAB7A and LAMTOR1 (PubMed:36476874). Acts as a positive regulator of the mTORC1 signaling by mediating deubiquitination of LAMTOR1, thereby promoting the association between LAMTOR1 and the lysosomal V-ATPase complex and subsequent activation of the mTORC1 complex (PubMed:36476874). |
| Cellular Location | Golgi apparatus membrane; Lipid-anchor |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Paulding C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2507-2511(2003).
Sha J.H.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Scanlan M.J.,et al.Int. J. Cancer 83:456-464(1999).
Olsen J.V.,et al.Cell 127:635-648(2006).
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¥ 1,250.00
Cat# AP21949a
