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Olfm1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
- 背景知识
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q99784 |
| Other Accession | Q62609, O88998, Q9IAK4 |
| Reactivity | Human |
| Predicted | Mouse, Rat, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55343 Da |
| Antigen Region | 71-100 aa |
| Gene ID | 10439 |
|---|---|
| Other Names | Noelin, Neuronal olfactomedin-related ER localized protein, Olfactomedin-1, OLFM1, NOE1, NOEL1 |
| Target/Specificity | This Olfm1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human Olfm1. |
| Dilution | WB~~1:2000 IHC-P~~N/A E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Olfm1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OLFM1 |
|---|---|
| Synonyms | NOE1, NOEL1 |
| Function | Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity). |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:O88998}. Synapse {ECO:0000250|UniProtKB:O88998}. Endoplasmic reticulum {ECO:0000250|UniProtKB:O88998}. Cell projection, axon {ECO:0000250|UniProtKB:O88998}. Perikaryon {ECO:0000250|UniProtKB:O88998} |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Olfm1 shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of this protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue.
REFERENCES
Yokoyama M.,DNA Res. 3:311-320(1996).
Yu W., Genome Res. 7:353-358(1997).
Liu T.,J. Proteome Res. 4:2070-2080(2005).
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