IMMT Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
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Application ![]()
| WB, IHC-P, FC, E |
---|---|
Primary Accession | Q16891 |
Other Accession | Q3KR86, Q8CAQ8 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 83678 Da |
Antigen Region | 438-467 aa |
Gene ID | 10989 |
---|---|
Other Names | MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89, IMMT, HMP, MIC60, MINOS2 |
Target/Specificity | This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human IMMT. |
Dilution | WB~~1:1000 IHC-P~~1:100~500 FC~~1:10~50 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | IMMT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IMMT |
---|---|
Synonyms | HMP, MIC60, MINOS2 |
Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.

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