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>   首页   >   产品   >   一抗   >   癌症   >   BACH1 Antibody   

BACH1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, IC
Primary Accession O14867
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 81958 Da
Additional Information
Gene ID 571
Other Names Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303, BACH1
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BACH1. The exact sequence is proprietary.
Dilution WB~~1:1000
IHC~~1:100~500
IF~~1:50~200
IC~~N/A
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name BACH1 {ECO:0000303|PubMed:9544839, ECO:0000312|HGNC:HGNC:935}
Function Transcriptional regulator that acts as a repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:24035498}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.

REFERENCES

Blouin J.-L.,et al.Hum. Genet. 102:282-288(1998).
Ohira M.,et al.Genomics 47:300-306(1998).
Taudien S.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Hattori M.,et al.Nature 405:311-319(2000).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).

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