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>   首页   >   产品   >   一抗   >   信号转导   >   Carbonic Anhydrase 5A Antibody   

Carbonic Anhydrase 5A Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP
Primary Accession P35218
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 34750 Da
Additional Information
Gene ID 763
Other Names Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA, CA5A, CA5
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Carbonic Anhydrase 5A. The exact sequence is proprietary.
Dilution WB~~1:1000
IP~~N/A
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CA5A (HGNC:1377)
Synonyms CA5
Function Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:24530203, PubMed:8356065). Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles (PubMed:24530203).
Cellular Location Mitochondrion.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Reversible hydration of carbon dioxide. Low activity.

REFERENCES

Nagao Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7623-7627(1993).
Nagao Y.,et al.Genomics 28:477-484(1995).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Temperini C.,et al.Chemistry 12:7057-7066(2006).
Temperini C.,et al.J. Med. Chem. 49:3019-3027(2006).

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