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>   首页   >   产品   >   一抗   >   精选抗体   >   Anti-p18 INK4c Antibody   

Anti-p18 INK4c Antibody

     
  • 1 - Anti-p18 INK4c Antibody AP51074
    Western blot analysis of p18 INK4c expression in mouse lung (A), mouse liver (B), rat lung (C), rat liver (D) whole cell lysates. (Predicted band size: 18 kD; Observed band size: 18 kD)
  • 19 - Anti-p18 INK4c Antibody AP51074
    Immunohistochemical analysis of p18 INK4c staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession P42773
Reactivity Human, Mouse, Rat, Mk
Host Rabbit
Clonality Polyclonal
Calculated MW 18127 Da
Additional Information
Gene ID 1031
Other Names CDKN6; Cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p18 INK4c. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
IHC~~1:100~500
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name CDKN2C
Synonyms CDKN6
Function Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Tissue Location Highest levels found in skeletal muscle. Also found in pancreas and heart
Research Areas

REFERENCES

Guan K.-L.,et al.Genes Dev. 8:2939-2952(1994).
Blais A.,et al.Biochem. Biophys. Res. Commun. 247:146-153(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Venkataramani R.,et al.Nat. Struct. Biol. 5:74-81(1998).
Li J.,et al.Biochemistry 38:2930-2940(1999).

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