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>   首页   >   产品   >   一抗   >   信号转导   >   Collagen 3 alpha 1 Antibody   

Collagen 3 alpha 1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P02461
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 138564 Da
Additional Information
Gene ID 1281
Other Names Collagen alpha-1(III) chain, COL3A1
Dilution WB~~1:1000
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name COL3A1
Function Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

REFERENCES

Ala-Kokko L.,et al.Biochem. J. 260:509-516(1989).
Valkkila M.,et al.Matrix Biol. 20:357-366(2001).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Benson-Chanda V.,et al.Gene 78:255-265(1989).

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