癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-VWA5A Antibody
- 产品详情
- 实验流程
Application 
| WB, IF/IC |
|---|---|
| Primary Accession | O00534 |
| Reactivity | Human, Mouse, Rat, Mk |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 86489 Da |
| Gene ID | 4013 |
|---|---|
| Other Names | BCSC1; LOH11CR2A; von Willebrand factor A domain-containing protein 5A; Breast cancer suppressor candidate 1; BCSC-1; Loss of heterozygosity 11 chromosomal region 2 gene A protein |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human VWA5A. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) IF/IC~~N/A |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | VWA5A |
|---|---|
| Synonyms | BCSC1, LOH11CR2A |
| Function | May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis. |
| Tissue Location | Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Martin E.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:11517-11522(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Monaco C.,et al.Genomics 46:217-222(1997).
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