癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-BRN3C Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q15319 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37052 Da |
| Gene ID | 5459 |
|---|---|
| Other Names | BRN3C; POU domain, class 4, transcription factor 3; Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BRN3C. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | POU4F3 |
|---|---|
| Synonyms | BRN3C |
| Function | Acts as a transcriptional activator (PubMed:18228599). Acts by binding to sequences related to the consensus octamer motif 5'- ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity). |
| Cellular Location | Nucleus. Cytoplasm Note=Preferentially localized in the nucleus |
| Tissue Location | Brain. Seems to be specific to the retina. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Xiang M.,et al.J. Neurosci. 15:4762-4785(1995).
Vahava O.,et al.Science 279:1950-1954(1998).
Collin R.W.J.,et al.Hum. Mutat. 29:545-554(2008).
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¥ 1,250.00
Cat# AP51700
