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Anti-RPS19 Antibody

     
  • 1 - Anti-RPS19 Antibody AP51706
    Western blot analysis of RPS19 expression in HEK293T (A), K562 (B), SHSY5Y (C), mouse liver (D), mouse testis (E), rat liver (F), rat testis (G) whole cell lysates. (Predicted band size: 16 kD; Observed band size: 16 kD)
  • 19 - Anti-RPS19 Antibody AP51706
    Immunohistochemical analysis of RPS19 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession P39019
Reactivity Human, Mouse, Rat, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 16060 Da
Additional Information
Gene ID 6223
Other Names 40S ribosomal protein S19
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RPS19. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
IHC~~1:100~500
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name RPS19 (HGNC:10402)
Function Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Required for pre- rRNA processing and maturation of 40S ribosomal subunits (PubMed:16990592). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
Cellular Location Cytoplasm. Nucleus, nucleolus
Tissue Location Higher level expression is seen in the colon carcinoma tissue than normal colon tissue
Research Areas

REFERENCES

Kondoh N.,et al.Cancer Res. 52:791-796(1992).
Draptchinskaia N.,et al.Nat. Genet. 21:169-175(1999).
Vladimirov S.N.,et al.Eur. J. Biochem. 239:144-149(1996).
Bienvenut W.V.,et al.Submitted (DEC-2009) to UniProtKB.
Kenmochi N.,et al.Genome Res. 8:509-523(1998).

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